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Home >> Health >> Conditions and Diseases >> Neurological Disorders >> Muscle Diseases >> Stiff-Person Syndrome |
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Foremost described by Moersch & Woltman at a Mayo Clinic in 1956,stiff human syndrome (SPS) occurs as uncommon neurologic disorder of unknown etiology. Victims by owning a sickness own household budget progressive, fluctuating tonic contractions of completely muscles, particularly a axial muscular structure. Inability to hike & paralysis quickly ensues; death unremarkably occurs six to twelve months fallowing diagnosing. Coarse of action is mostly palliative with muscle relaxants such as benzodiazepines, which lose their effectiveness as a malady progresses. Because several patients using SPS own circulating antibodies to glutamic acid decarboxylase, an autoimmune genesis to the disease has been postulated. In the absence of double-blind, placebo-controlled class A trials to determine treatment efficaciousness, a select few authorities recommend humane lawsuits of immunosuppressive therapy, plasmapheresis or intravenous immunoglobulin infusion.
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MCW HealthLink An article about Stiff-person syndrome, a rare progressive neurological disorder. Stiff-Person Syndrome Information sheet compiled by National Institute of Neurological Disorders and Stroke. NORD: Stiff Person Syndrome Offers synonyms, a general discussion and further resources. Stiffman Syndrome Also known as Stiff Person Syndrome or Moersch-Woltman. A rare, progressive neurological disease with symptoms of severe spasm, rigidity and falls. Find information and a personal story. |
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